Research Associate in the department of Biomedical Engineering at the Cleveland Clinic Foundation.

Contents 1 Education 2 Current Research Projects 3 Other Research Interests 4 Publications 5 Manuscripts in Preparation 6 Abstracts presented at peer-reviewed conferences 7 Patent Applications 8 Contact Info

[edit] Education

• B.S. in Computer and Systems Engineering from Universidad Autónoma de Chihuahua.
• M.S. in Biomedical Engineering from Case Western Reserve University.
• Ph.D. in Biomedical Engineering from Case Western Reserve University. Dissertation

[edit] Current Research Projects

• Identification of brain fiber pathways and volumes of tissue activated with Deep Brain Stimulation (DBS) and their relationship to therapeutic and non-therapeutic stimulation.
• Optimal fitting of three-dimensional brain atlas to patient-specific neuroanatomy and electrophysiological data for surgical targeting.
• Finite element models of multipolar DBS

[edit] Other Research Interests

• Neurostimulation Systems
• Biomechanical and Neuromuscular modeling
• Artificial Intelligence
• Optimization

[edit] Publications

• Luján J.L., Noecker A.M., Butson C.R., Cooper S.E., Walter B.L., Vitek J.L., McIntyre C.C. "Automated 3-Dimensional Brain Atlas Fitting to Microelectrode Recordings from Deep Brain Stimulation Surgeries." Stereotact Funct Neurosurg. 2009 Jun 26;87(4):229-240. PMID:19556832
• Luján J.L., Crago P.E. “Automated optimal coordination of multiple-degree-of-freedom musculoskeletal actions in feedforward neuroprostheses”. IEEE Transactions in Biomedical Engineering. January 2009. PMID:19224731
• Luján J.L., Chaturvedi A., McIntyre C.C. “Tracking the mechanisms of deep brain stimulation for neuropsychiatric disorders”, Frontiers in Bioscience. 2008. May 1;13:5892-904 PMID:18508630
• Luján J.L., Crago P.E. "Computer-based test-bed for clinical assessment of hand/wrist feed-forward neuroprosthetic controllers using artificial neural networks.", Med Biol Eng Comput. 2004 Nov;42(6):754-61. PMID:15587466

[edit] Manuscripts in Preparation

• Luján J.L., Chaturvedi A., Malone D., Rezai A., McIntyre C.C. “Axonal Pathways and Volume of Tissue Activated by Therapeutic Deep Brain Stimulation for Neuropsychiatric Disorders and Their Correlation to Therapeutic Outcomes”. (Target Journal – Biol Psychiatry).
• Luján J.L., Noecker A.M., Chaturvedi A., Cooper, S.E., Vitek, J.L., McIntyre, C.C., “Automated 3D brain atlas fitting to magnetic resonance images and microelectrode recordings from deep brain stimulation surgeries”. (Target Journal – Stereotact Funct Neurosurg).
• Chaturvedi A., Luján J.L., McIntyre, C.C., “Characterization of the volumes of tissue activated during multipolar deep brain stimulation”. (Target Journal – Journal of Neural Engineering).

[edit] Abstracts presented at peer-reviewed conferences

• Luján J.L., Chaturvedi A., Malone D., Rezai A.R., McIntyre, C.C., “Axonal Pathways Activated by Deep Brain Stimulation for Neuropsychiatric Disorders and Their Correlation to Therapeutic Outcomes". Society for Neuroscience (SFN) Meeting. Chicago, IL. October 17-21, 2009.
• Luján J.L., Chaturvedi A., Malone D., Rezai A.R., McIntyre, C.C., “Volumes of Tissue Activated by Deep Brain Stimulation for Neuropsychiatric Disorders and Their Correlation to Therapeutic Outcomes". 15th Quadrennial Meeting of the World Society for Stereotactic and Functional Neurosurgery (WSSFN), Toronto, Ontario, Canada. May 24-27, 2009.
• Luján J.L., Noecker A.M., Butson C.R., Cooper S.E., Walter B.L., Vitek J.L., McIntyre, C.C., “Automated 3D Brain Atlas Fitting to Magnetic Resonance Images and Microelectrode Recordings From Deep Brain Stimulation Surgeries”. NIH Neural Interfaces Conference, Cleveland, OH. June 16-18, 2008.
• Luján J.L., Chaturvedi A., Malone D., Rezai A.R., McIntyre, C.C., “Axonal Pathways Activated by Deep Brain Stimulation for Neuropsychiatric Disorders". Biennial Meeting of the ASSFN, Vancouver, B.C., June 1-4, 2008. Canada.
• Luján J.L., Noecker A.M., Butson C.R., Cooper S.E., Walter B.L., Vitek J.L., McIntyre, C.C., “Automated 3D Brain Atlas Fitting to Magnetic Resonance Images and Microelectrode Recordings From Deep Brain Stimulation Surgeries”. Biennial Meeting of the ASSFN, Vancouver, B.C., June 1-4, 2008. Canada.
• Noecker A.M., Luján J.L., Miocinovic S., Butson C.R., McIntyre C.C. "Human Cicerone: Deep Brain Stimulation Neurosurgical Research Software System". Biennial Meeting of the ASSFN, Vancouver, B.C., June 1-4, 2008. Canada.
• Luján J.L., Noecker A.M., Butson C.R., Cooper S.E., Walter B.L., Vitek J.L., McIntyre, C.C. “Automated 3D brain atlas fitting to microelectrode recordings from deep brain stimulation surgeries" SFN Meeting. November 3-7, 2007. San Diego, CA.
• Luján J.L., Crago P.E. "Automated Optimal Coordination Of Electrically Stimulated Muscles For Neuroprostheses", Proceedings of the Annual Fall Meeting of the Biomedical Engineering Society (BMES), October 11-14, 2006, Chicago, Illinois.
• Luján J.L., Crago P.E. “Feed-forward control of neuroprosthetic systems with multiple degrees of freedom" NIH NINDS Neural Interfaces Workshop. September 7-9, 2005. Bethesda, MD.
• Luján J.L., Crago P.E. “Unique solution for feed-forward control of neuroprosthetic systems characterized by redundant muscles acting on multiple degrees of freedom" XXth Congress of the International Society of Biomechanics and 29th Annual Meeting of the American Society of Biomechanics, July 31 - August 5, 2005, Cleveland, Ohio
• Luján J.L., Crago P.E. “Optimal solution training of artificial neural networks for feed-forward control of neuroprostheses", Thirty Four NIH NINDS Neural Prostheses Workshop, October 21-23 , 2003. Bethesda, MD.
• Luján J.L., Crago P.E. “Feed-forward controller for a hand/wrist neuroprosthesis using artificial neural networks” Proceedings of the Annual Fall Meeting of the Biomedical Engineering Society (BMES), October 4-7, 2001. Durham, North Carolina.
• Luján J.L., Crago P.E. “Computer-Based Feed-Forward Controller for a Hand/Wrist Neuroprosthesis Using Artificial Neural Networks”, Proceedings of the 6th Annual Conference of the International Functional Electrical Stimulation Society. June 17-20, 2001. Cleveland, Ohio

[edit] Patent Applications

• U.S. Patent Application “Automated 3D brain atlas fitting using intra-operative neurophysiological data”. CCF-8861, U.S. Provisional Patent No. 60/985,718. “Automated 3D brain atlas fitting using microelectrode recordings”. October 12, 2006. Inventors: J. Luis Lujan, Cameron C. McIntyre.
• CCF Invention disclosure form (IDF) submitted. “Method for predicting volumes of neuronal tissue activation” November 1, 2008. Inventors: J. Luis Lujan, Ashutosh Chaturvedi, Cameron C. McIntyre.

[edit] Contact Info

email: jll7 [at] case [dot] edu

Phone: 216.445.8857