Course:SOMBlock3IQ1/Week 1/Case 11

Contents

[edit] Case 11: Liver & Ethanol

[edit] 1. Trace the pathways of alcohol metabolism in the liver and explain the affect of ethanol metabolism on the TCA cycle and the pathways of fatty acid metabolism and gluconeogenesis.

[edit] 2. List the amount of alcohol necessary to cause Alcohol Liver Disease.

[edit] 3. Use the CAGE questions to identify/diagnose if alcohol consumption is a problem in a patient.

[edit] 4. List the two scoring systems to define the prognosis of Alcohol Liver Disease and name the cofactors that contribute to liver disease in alcoholics.

[edit] 5. Describe the current inflammatory hypothesis of liver injury by chronic alcohol consumption.

[edit] 6. Describe the histopathology of alcoholic liver disease.

[edit] 7. Explain how alcohol may potentiate acetaminophen toxicity in the liver.

[edit] 8. List the pharmacologic treatment for severe alcoholic hepatitis.

[edit] 9. Compare and contrast the effects of binge drinking versus heavy regular intake of ethanol.

[edit] 10. List the behavioral and pharmacologic therapies used to treat alcohol addiction.

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